Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1
نویسندگان
چکیده
منابع مشابه
Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1.
The stress-activated protein kinase (SAPK, alternatively JNK) is activated rapidly by cell stress stimuli such as inflammatory cytokines and oxidative stress, and more slowly by the initiation of the apoptotic cell death response by events such as ligation of the Fas protein. Mitogen-activated protein kinase/Erk kinase kinase-1 (MEKK1) is an activator of SAPK, serving as a SAPK-kinase-kinase th...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1998
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.95.10.5595